The Immortal Life of Henrietta Lacks
The Brain Institute of America
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Hello Institute followers
Please see a link below, to our new paper published from the Institute.
This review highlights the role of long noncoding RNAs (lncRNAs) in cancer metastasis!
Signaling pathways are tightly controlled systems that regulate the appropriate timing of gene expression required for the differentiation of cells down a particular lineage essential for proper tissue development. Proliferation, apoptosis and metabolic pathways are just a few examples of the signaling pathways that require fine-tuning, so as to control the proper development of a particular tissue type or organ system. An estimated 70% of the genome is actively transcribed, only 2% of which codes for known protein-coding genes. Long noncoding RNAs (lncRNAs) in particular, are a large and diverse class of RNAs > 200 nucleotides in length, and not translated into protein.
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