New Paper from the Institute The Brain Institute of America

Hello Institute followers

Please see a link below, to our new paper published from the Institute.

This review highlights the role of long noncoding RNAs (lncRNAs) in cancer metastasis!

Review –

Abstract

Signaling pathways are tightly controlled systems that regulate the appropriate timing of gene expression required for the differentiation of cells down a particular lineage essential for proper tissue development. Proliferation, apoptosis and metabolic pathways are just a few examples of the signaling pathways that require fine-tuning, so as to control the proper development of a particular tissue type or organ system. An estimated 70% of the genome is actively transcribed, only 2% of which codes for known protein-coding genes. Long noncoding RNAs (lncRNAs) in particular, are a large and diverse class of RNAs > 200 nucleotides in length, and not translated into protein.

Want to know more….